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time 132 (n) 132 (n) Improvement, RR [CI] High Levels Low Levels Kayar all -32% 1.32 [0.76-2.28] death 182/539 10/39 All studies -5% 1.05 [0.91-1.20] 182/671 10/171 5% higher risk 2 vitamin B12 COVID-19 sufficiency studies c19 early .org July 2026 Tau 2 = 0.00, I 2 = 0.0%, p = 0.53 Effect extraction pre-specified (most serious outcome, see appendix) Favors vitamin B12 Favors control Download Image 0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Jang 78% 0.22 [0.05-0.94] no recov

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Bacterial overgrowth in the small intestine may similarly present with both symptoms

Thus, and for consistency with previous studies (Bach et al

[1] Because of this variability, recent systematic reviews often conclude that evidence of efficacy is inconclusive or limited

20, 21 These associations suggest that there may be a systemic dysregulation in some patients