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In human lung fibroblasts an upregulation of COX-2 expression and subsequent production of PGE2 was observed in normal and stress-induced senescence, while arachidonic acid supplementation further enhanced this observation and accelerated the incidence of key senescent features (Wiley et al., 2021)

Hampshire, A

10.1038/nri.2017.52 181 SunC.WuQ.ZhangX.HeQ.ZhaoH

Therefore, this section of this review article briefly highlights a few rat models involving this neurotoxic peptide

4.5 Redox Balance Glutamine plays a crucial role in maintaining cellular redox homeostasis by supporting the synthesis of glutathione (GSH), one of the major antioxidants in the cell
