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(2008) described the discovery and characterization of the tissue-protective EPO receptor (now called the innate repair receptor) and demonstrated that engineered EPO derivatives lacking erythropoietic activity retained cytoprotective signaling, laying the foundation for ARA-290 development [2]

Reduced butyrate levels in CFS/ME patients may contribute to increased gut permeability (leaky gut), allowing microbial products like LPS to enter the circulation and trigger systemic immune activation (Wang J.-H

Simic 2014)

A questionnaire study with Dutch GPs found that they did not consider endometriosis as the diagnostic impression from the first consultation with symptoms