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Description
Cell Death Dis (2022) 13(4):355
These TcdA and TcdB units catalyze the monoglucosylation of the threonine 35/37 residue of small GTP-binding proteins Rho, Rac and Cdc42 within target cells, and thus modulate several physiological cellular events resulting in cell death
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elegans , this pathway evolves in parallel with the insulin signaling pathway till it converges to DAF-16 which is phosphorylated by JNK-1 (113)
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However, it is also commercially produced through chemical synthesis or biotechnological fermentation to achieve pharmaceutical-grade purity
