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Figure 2 Consistent with this idea, glutathione, a tripeptide molecule (cysteine, glutamic acid, and glycine) and the most abundant endogenous free radical scavenger in humans, was the first antioxidant evaluated for the treatment of NIHL (Yamasoba et al., 1998

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Robert, L., VanEtten, R

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Iron and pro-inflammatory cytokines activate the transcriptional factor nuclear factor-B (NF-B), which enhances the production of inducible nitric oxide synthase (iNOS), converting arginase into NO [307, 308]

Adaeze K., Lagos
