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There is mounting evidence for the role of oxidative stress in the pathophysiology of depression

Once the fatty acids pass into the mitochondria, they can be oxidized ("burned") to generate ATP

The company has conducted in vitro studies demonstrating a 30% increase in glutathione levels when cells are treated with their lithium orotate-glutathione precursor complex compared to individual components[1]

Other studies find that HG induces endogenous antioxidant systems [10, 18, 23]

Significant reductions in serum levels of total IS, p-CS, IL-6, and malondialdehyde (as markers of inflammation and oxidative stress, respectively) were observed in 30 patients with ESKD undergoing hemodialysis treatment after an 8-week administration of synbiotics containing 2 10 11 (CFU)/g of Lactobacillus acidophilus La-14 and FOS (Kuskunov et al., 2023)

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