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In addition, excessive oxidative stress induces irreversible damage to mitochondria, diminishing organelle integrity

Accessed October 27, 2025

EZH2 inhibitors are reported to exert therapeutic effects on various kidney diseases, including renal cell carcinoma, AKI, renal fibrosis, diabetic nephropathy, lupus nephritis, and renal transplant rejection [19, 20]

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Furthermore, as a cyto-protectant, melatonin helps alleviate several COVID-19 comorbidities, including T2DM, metabolic syndromes, and both ischemic as well as non-ischemic CVD 657

The compound i
