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1A for a schematic overview of the differentiation)

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Acknowledgments We would like to thank Professor Jianye Dai (Faculty of Pharmacy, Lanzhou University) and Professor Bin Luo (Faculty of Public Health, Lanzhou University) for help in quality of figures and article structure

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These compounds are not approved by the U.S Food and Drug Administration (FDA) for weight loss, but healthcare providers prescribe these compounds off-label for weight loss and improving metabolic health

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