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Guieu, R

Erguder IB, Ucar A, Ariturk I, et al

In vivo studies have shown that mitochondrial transplantation can enhance neuronal survival, reduce oxidative stress, and improve behavioral outcomes in models of Parkinsons disease, stroke, and traumatic brain injury [6] These effects have been achieved using various delivery methods, including direct intracerebral injection and intranasal administration, which overcome the limitations of in vitro co-incubation by enabling physiologically relevant uptake mechanisms

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doi: 10.1007/s00011-009-0116-5

In BAT mitochondria, closely packed cristae might enforce prioritized CK/ANT/ATP synthase cross-talk, while loosely arranged cristae in skeletal muscle can buffer this spatial coordination requirement
