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The research also identified a mutation in DNMT3B leading to the mislocalization of H3K4me1 activity, resulting in hypermethylation of active promotersa finding closely related to the immunodeficiency phenotype of ICF syndrome, particularly in genes involved in B-cell receptor-mediated maturation pathways (51)
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Unpaired, two-tailed students t -tests were performed to assess statistical significance with significance levels as indicated
Springer Science & Business Media (2013)
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