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Early signs are vague and easy to dismiss, but by the time severe symptoms appear, nerve damage may already be present

Bibcode:1979AcCrB..35.3089B

GeroScience 10.1007/s11357-023-00919-x (2023)

Older Adults Aging can lead to decreased stomach acid production, impacting the absorption of B12 from food sources

24 25 Some patients may experience recurrence or worsening of symptoms when the interval between injections is extended or extended too quickly, and report that continuation of frequent intramuscular hydroxocobalamin injections, varying between twice weekly and once every three to four weeks, 65 is needed to remain asymptomatic