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Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis

Transcriptional regulatory axis of HER2-ELF3-KRAS as a therapeutic target for KRAS G13D CRCs G13D Building on our findings that HER2 is a predictive biomarker and prognostic factor for CTX response in KRAS G13D CRCs, we investigated potential strategies to regulate HER2 as a novel therapeutic approach for CRC patients harboring the KRAS G13D mutation

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