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The disruption of OPTN E50K induced autophagy affected the degradation of TDP-43, which led to glaucomatous retinal neurodegeneration [147]

Children are particularly sensitive to lead intoxication, both acute and chronic, and there is no identified safe level of lead exposure in children

This is where the concept of bioavailability becomes vital

Trends in Neurosciences , 40(10), 625-636

Slides were then counterstained with Gill-2 hematoxylin, dehydrated, cleared and mounted between slides and coverslips with Pertex

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