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In mice fed HFD, TMAO supplementation exacerbated glucose intolerance, induced adipose tissue inflammation, and promoted insulin resistance (154)

Busquets S, Perez-Peiro M, Salazar-Degracia A, Argiles JM, Serpe R, Rojano-Toimil A, Lopez-Soriano FJ, Barreiro E

Szab K, Nagy Z, Juhsz V, Zolnerciks JK, Csorba A, Tmr Z, Molnr , Pdr P, Johnson W, Bery E, Krajcsi P (2017) Species specificity profiling of rat and human organic cation/carnitine transporter Slc22a5/SLC22A5 (Octn2/OCTN2)

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Mild digestive discomfort may occur at high doses, but it is generally safe for healthy individuals

Sin embargo, estas conversiones dependen de la microflora y de la afinidad de las diferentes aminas cuaternarias por las poblaciones microbianas intestinales