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New Phytol 225:11661180

Extending the lifespan of long-lived mice

Chronic oxidative stress is linked to a wide range of diseases, including: Cardiovascular disease : ROS damage endothelial cells lining blood vessels, promoting atherosclerosis and hypertension.[9] Neurodegenerative disorders : Oxidative damage to neurons is a key driver in conditions like Alzheimers, Parkinsons and ALS.[10] Diabetes and insulin resistance : Oxidative stress impairs insulin signaling and worsens glycemic control.[10] Cancer : DNA mutations caused by free radical damage may initiate or accelerate tumor development.[11] Autoimmune conditions : Oxidative stress can trigger inflammatory pathways, contributing to immune dysregulation.[9] Even outside of these conditions, oxidative stress contributes to fatigue, slower recovery, immune suppression and premature aging at the cellular level

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AHK-Cu (Alanyl-Histidyl-Lysine Copper) is a copper-binding tripeptide widely studied in scientific research involving hair follicle biology, dermal papilla cell activity, skin biology, tissue regeneration, and cellular signalling pathways

Statins could facilitate GLUT1 transcription, while repress GLUT4