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Development of polymeric nanoparticles for bloodbrain barrier transferstrategies and challenges

To overcome the problem, prodrugs activated only after oral absorption were developed
In the druggability evaluation, 12 proteins (CBR3, GSTO1, HHIP, IGF2R, MMP10, TLR2, CST3, FSTL5, GMPR2, IFI16, MAPK9, and NEO1) were predicted as druggable targets (Fig
W swojej czsteczce oprcz atomw wgla, wodoru i azotu zawiera atom siarki
Peptides bind in the W-box as observed in the crystal structures
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