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A two-sample t -test was performed, assessing significant differences between treated and control samples

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Moreover, GPX3 deficiency also led to the downregulation of Nrf2, a negative upstream regulator of ferroptosis, suggesting that the antagonistic effect of GPX3 on ferroptosis in prostate cells was related to Nrf2

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A novel Omega-class glutathione S-transferase gene in Apis cerana cerana : molecular characterisation of GSTO2 and its protective effects in oxidative stress