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The above-presented body of literature in this review strongly supports the fact that there are several pharmacologic agents available to prevent, at least in part, this disability

Glutathione possesses a unique gamma-peptide bond between the gamma-carboxyl group of glutamate and the alpha-amino group of cysteine, conferring resistance to degradation by most intracellular peptidases while remaining susceptible to gamma-glutamyltransferase

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Spampinato et al ., 2018

10.1016/s0021-9258(18)71625-6 33 JeongY

Wistar rats (55/sex per dose) were exposed for life (6 h/day, 5 days/week, for 28 months) to acetaldehyde concentrations of 1350, 2700, or 1800-5400 mg/m 3 (the last concentration was gradually reduced from 5400 mg/m 3 in week 20 to 1800 mg/m 3 in week 52)