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Ferroptosis induces ER stress, while ER stress exerts dual effects on ferroptosis (Huang et al

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[DOI] [PubMed] [Google Scholar] 5.Mansukhani KA

Mechanistically, permeation enhancement is typically achieved through transient modulation of epithelial tight junctions to increase paracellular transport, alteration of membrane organisation to facilitate transcellular diffusion, and may also influence local mucus-drug interactions or enzymatic stability depending on excipient chemistry and exposure profile (Maher et al., 2019)