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J Am Acad Dermatol 85(5):12671273
Oslowski CM, Hara T, OSullivan-Murphy B, Kanekura K, Lu S, Hara M, Ishigaki S, Zhu LJ, Hayashi E, Hui ST, Greiner D, Kaufman RJ, Bortell R, Urano F (2012) Thioredoxin-interacting protein mediates ER stress-induced cell death through initiation of the inflammasome
This redox activity influences superoxide dismutase (SOD) mimetic function, catalyzing the dismutation of superoxide radicals (O2) to hydrogen peroxide and molecular oxygen
The role of NQO1 in chemoprotection has been extensively reviewed (Ernster, 2000) and there is detailed information available regarding NQO1 structure and mechanism (Hosoda et al., 1995
2000 Aug;22(5):307-14
