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Whether such changes in 24-h cortisol levels are associated with changes in, CRH, ACTH, glucocorticoid receptor sensitivity and/or down regulation of receptor number require follow-up non-human animal models and additional human studies of chronic circadian misalignment

Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons

Funding: The work was supported by Terry Fox Cancer Research Funds and Faculty of Medicine and Health Sciences Research Committee fund from UAE University

This impairment occurs through the reduction of insulin-stimulated tyrosine phosphorylation of the insulin receptor and IRS-1, an increase in serine phosphorylation of IRS-1, and, hence, inhibition of Akt phosphorylation

2D-gel based proteomics unravels neurogenesis and energetic metabolism dysfunction of the olfactory bulb in CUMS rat model

Enoch, 2008