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Based on our experience, a hurdle in the expanded clinical use of NAC is that there is no clear characterization of what constitutes a response to NAC in patients with different diseases
Sports Med 47 , 23412361 (2017)
Due to the number of members in this superfamily, there is a wide range of functions associated with these enzymes including: glutathione peroxidase activity, prostaglandin synthesis, and roles in thiolysis and isomerization reactions [86]
In fact, a therapy combining tretinoin with hydroquinone is often prescribed for a powerful synergistic effect
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10.1038/tp.2016.156 Transl Psychiatry
