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Specifically, 5-Aza affects the expression levels of DNMT1 and can be incorporated into both DNA and RNA, whereas DAC targets both DNMT1 and DNMT3A and is incorporated exclusively into DNA [295]

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This suggested that the observed reductions in GPX4 protein levels were likely due to a post-translational mechanism

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doi: 10.1088/1361-6579/aa724d

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