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Dornase alpha compared to hypertonic saline for lung atelectasis in critically Ill patients

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In internally driven apoptosis, B-cell lymphoma-2 (Bcl2) associated X protein (BAX) activity drives the mitochondrial release of cytochrome C to stimulate the caspase cascade that triggers apoptosis [89]

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121 MadhukritiRoyA.PanditS.KumarA.SharmaK.RajS.et al (2025)

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Conversely, SIRT3 overexpression has the opposite effects, 105 suggesting that SIRT3 inhibits AKT-dependent mitochondrial metabolism and EMT, thereby promoting ferroptosis

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