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Description
As women exit their puberty estrogen production tapers off

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Taken together, these results suggest that CPP-CAND inhibited the FOXO4-p53 interaction in the nucleus, which enabled the extranuclear transport of p53 and selectively induced apoptosis in senescent cells

Besides its diagnostic potential, aberrant DNA methylation of specific CpGs has been also proposed as a predictive and prognostic GC biomarker

doi: 10.1002/phar.2305 204

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