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J Pediatr.Gastroenterol.Nutr
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The small-molecule integrin antagonist THR-687 has shown preclinical efficacy in reducing choroidal neovascularization (Hu et al., 2019) and demonstrated tolerability and anatomical benefit in early-phase trials for DME (Khanani et al., 2021)

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Adems, acta como un potente anticatablico, disminuyendo la destruccin de masa muscular por dietas adelgazantes incorrectas

However, more investigation is necessary for definitive conclusions