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doi:10.1002/smll.201700983 74

Energy metabolism, which is critical for each organism, was significantly reduced in AST1D rats, especially in serum and hippocampus

Its anti-inflammatory mechanisms include reducing TNF-alpha production, downregulating NF-kB activation, and decreasing oxidative stress through enhanced antioxidant enzyme activity

To assess these hypotheses, a variety of senolytic drugs were tested in vitro (in a test tube) on BM-MSC from SLE patients and from lupus model (NZB/W) mice

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