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TB500 is a synthetic version of thymosin beta-4, which is believed to play a role in the repair and regeneration of damaged cells and tissue

(PubMed) Clarke R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM

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Markers of Liver Regeneration-The Role of Growth Factors and Cytokines: a Systematic Review

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Rectal absorption could be also compared to transdermal (through the skin) absorption due to the anatomy of the rectum