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This increase in ROS triggers mitochondrial dysfunction, further exacerbating oxidative stress and promoting cell death through both necroptosis and ferroptosis pathways (Figure 5) (Table 1, we present a comparative analysis of other proteins involved in cancer treatment, particularly those influencing ER stress or ferroptosis

Results showed that the penetration level of diethyldithiocarbamate (DDC), the primary metabolite of DSF, was approximately 1.3 times higher in MC-based eye drops than in plain drops [63]

The rabbits presented with GHK-Cu peptide exhibited an apparent decline in neutrophil counts and increase in neovascularization

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However, luteolin's potential benefits in AD are primarily linked to the modulation of amyloid- accumulation and tau hyperphosphorylation, whereas in PD its effects are more closely associated with the inhibition of -synuclein aggregation, protection of dopaminergic neurons, and improvement of mitochondrial function, particularly at the level of complex I

[DOI] [Google Scholar] Risner, D