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This finding is devastating
We typically recommend B12 therapy for individuals who have been diagnosed with B12 deficiency or who may be at risk due to factors such as age, certain medical conditions, or a vegan or vegetarian diet
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On the other hand, for the L-NAME retrobulbar applicationinduced retinal ischemia model and BPC 157 therapy in rats, we should emphasize the point that animal studies per se may be cautious regarding their results, although the role of an animal model is indispensable (Vestergaard et al., 2019)
These data show the low reactivity of the free depsipeptides and confirm the chemical stability of cereulide as reported earlier 20,21,22
The clinical response to B12 treatment in SCD patients is expected to be better when large doses of B12 are administered more frequently than when B12 is administered less frequently [96]
