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The zeta potential of both fractions nanoparticles are close to each other and within the range of 30 to + 30 indicating large repulsive forces between particles that can prevent aggregation and ensure easy dispersion, indicating more stability in the suspension, where zeta potential is an index of nanoparticles stability, the higher the zeta potential, the more stable suspension is produced [51]

[DOI] [PubMed] [Google Scholar] [110].Schwartzman RJ, Alexander GM, Grothusen JR, Paylor T, Reichenberger E, Perreault M, Outpatient intravenous ketamine for the treatment of complex regional pain syndrome: a double-blind placebo controlled study, Pain 147(13) (2009) 10715
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