l carnitine for sperm health Male Fertility Supplements – Boost & Motility – Bird&Be Evaluation of L-Carnitine Potential in E N D

E N D Presentation Transcript L-Carnitine Charisma Garcia NFSC 345 Introduction Background Purported Benefits Mechanism of Action Evidence of Benefits Conflicting Research Safety Concerns Professional Position L-Carnitine Essential for Energy Production Naturally Occurs in the Human Body Synthesized in the Liver & Kidneys Derived from the amino acid, Lysine Produces 11-34mg/day (Sufficient to meet all needs!) Dietary L-Carnitine Red meat, dairy, fish, wheat, asparagus, avocado Omnivorous diet: 20-200mg/day (~75% absorbed) No proof of Dietary need exists L-Carnitine as a Supplement Liquid form,Tablets & Capsules Typical Dose: 1000-6000 mg/day ~20% absorbed by the body Generally non-toxic Intended population: Athletes Dieters Purported Benefits Primary Systemic Carnitine Deficiency A recessive gene mutation Cardiovascular Disease Alzheimers Disease Chronic Fatigue In the Elderly Population In Cancer Patients Fat Loss No Evidence EXERCISE PERFORMANCE

Pharmacokinetics of hydroxocobalamin in smoke inhalation victims

Oral and topical tranexamic acid provide many benefits to the skin, including decreased sensitivity to the sun and diminished hyperpigmentation

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The cysteine conjugate M2 represented 16.5% of circulating dose in the radiolabelled human ADME study (pooled, 0-48h) [9]

Current understanding and future perspectives of the roles of sirtuins in the reprogramming and differentiation of pluripotent stem cells