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They work as coenzyme in several biochemical reactions to activate enzyme reaction of corresponding protein by creating holoenzyme
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Dose Rate: Lambs: 0.5 mL at marking or weaning Sheep: 1.0 1.5 mL pre-lambing Calves: 2 3 mL from 2 months of age Cows: 4 6 mL pre-calving The frequency of dosing should be related to the severity of the deficiencies