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GPx3 is also one of the 25 known selenoproteins in humans, which harbor a unique selenocysteine found in the active site that utilizes glutathione as the primary reducing agent to remove oxidative compounds 31,32

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This occurs partly through metal ion (Fe 2 /Cu 2 )-mediated redox reactions generating OH [333]

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111 Bone disease Bone remodeling is involved in determining bone mass

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