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Long-term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy: the 3-year, multicenter, comparative Aldose Reductase Inhibitor-Diabetes Complications Trial

Certain populations, such as vegans, vegetarians, older adults, and those with pernicious anemia, may need to supplement with B12

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Fang Z, Xu Y, Liu G, Shao Q, Niu X, Tai W, et al

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reported cases of liver enzyme elevations during repeated ketamine treatments for chronic pain, with levels returning to normal upon drug discontinuation