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On the other hand, Byrne and colleagues examined the impact of increased colonic propionate production on brain anticipatory reward responses during the examination of food images, hypothesizing that increased propionate would reduce both reward responses and ad libitum calorie intake by promoting the release of anorexigenic gut hormones 69

PLoS ONE 4 , e4589 (2009)

Furthermore, they will directly capture 1 O 2 and inhibit lipid peroxidation by trapping lipid alkoxy radicals (Sharma et al., 2012)

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Similarly, excessive ONOO formation causes widespread nitration of host proteins (e.g., forming 3-nitrotyrosine), altering their function and driving pathology in chronic inflammatory and autoimmune diseases [13, 150]