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We strongly recommend it, but no - you do not have to have one if you choose not to, though we do explain why this is storngly recommended

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However, vitamin B12 can be stored in the liver for a long time, so it does not easily become deficient
Dufour E, Villard SS, Mellon V, et al

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IJBAMR 1(9):1826 Kim J et al (2019) Association between metformin dose and vitamin B12 deficiency in patients with type 2 diabetes
