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Furthermore, similar levels in expression of inflammatory markers such as TLR-signalling members and immune cell markers in muscle of LFD fed Cpt1b m/ mice and LFD fed control mice suggest that depletion of CPT1b indeed keeps inflammatory status in muscle as low as at the LFD level (10% calorie from fat) even in mice fed CHD (25% calorie from fat) or HFD (45% calorie from fat)

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The most common adverse events were mild-to-moderate headaches, similar in frequency to placebo groups