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Relative Contraindications: Injection into Fingers & Toes Historically, the injection of epinephrine containing solutions into end-artery structures such as fingers and toes has been widely discouraged due to the concern that prolonged vasoconstriction may cause vascular insufficiency resulting in tissue necrosis and permanent injury

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In contrast, although the 10 molL -1 SL treatment reduced MDA to the lowest value and induced massive accumulation of TPS, it led to a sharp decline in SPC