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Numerous studies have demonstrated the involvement of the NF-B pathway in the development of IBD

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10.1080/1061186X.2021.1909051 500 XiongY.HongH.LiuC.ZhangY

Mathew JP, Fontes ML, Tudor IC, Ramsay J, Duke P, Mazer CD, et al

Although being relatively understudied, B cells have been shown to exhibit both detrimental and protective effects in the ischemic brain

Topical NSAIDs (such as ibuprofen gel) offer localised pain relief with minimal systemic absorption and are recommended by NICE as first-line for localised joint pain
