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INTRODUCTION SEARCH STRATEGY EXISTING RESCUE THERAPIES FOR ASUC 1) Short-term Efficacy 2) Long-term Efficacy 3) Safety Profile 4) Dosing Schedule 1) Short-term Efficacy 2) Long-term Efficacy 3) Safety Profile 4) Dosing Schedule P = 0.24) [9]

6 Pharmacological therapies Treatment options can be categorised into chemically destructive, physically destructive, antiproliferative or immunostimulatory

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