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In some embodiments, the otic formulation or composition comprises about 5% by weight of the poloxamer

GHK (Gly-His-Lys) without copper is a simple tripeptide with a strong affinity for Cu(II) ions (log stability constant ~16.2), while GHK-Cu is the pre-formed 1:1 copper-peptide complex with distinct biological activity profiles

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CERTIFICATION LETTER Everglades City Community Center Project Recipient: Everglades City Location: 102 Copeland Avenue North, Everglades City, Florida 34139 Amount: $7,200,000 million Justification: The funding would be used for the construction of a new community center, which will serve residents in Everglades City and the eastern unincorporated Collier County communities of Chokoloskee Island, Copeland, Jerome, Lee Cypress, Ochopee, and Plantation Island