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With regards to the endoplasmic reticulum (ER) stress, Phospho-PERK (p-PERK) and ATF4 expression was decreased in the HF group, and only the HFD+NAC(112), but not HFD+NAC(16) group, showed significant improvement

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Poor diet, decreased liver function, and certain medications can impair this process

Consuming alcohol during peptide therapy can lead to reduced effectiveness of the treatment and even to the occurrence of side effects

Fasting blood glucose (FBG), glycosylated hemoglobin (HbA1c), C- peptide, total antioxidant capacity (TAC), superoxide dismutase (SOD), catalase (CAT), glutathione and thiobarbituric acid reactive substances (TBARS) at the baseline, and every 3 months thereafter were determined

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