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Estrogen dominance (common in perimenopause) can impair bile flow, which normally helps control bacterial populations in the small intestine

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Human iPSC-derived neuron and oligodendrocyte co-culture as a small-molecule screening assay for myelination

The combination produced 22.7% mean body weight loss versus approximately 2% with placebo (Aronne et al., 2025)

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The proposed master mechanism: epithalon binds to specific regions of DNA preferentially methylated cytosine residues and to histone proteins, which influences which genes are accessible for transcription