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The protein p53 encoded by this gene inhibits the development of tumors through the regulation of the cell cycle, apoptosis, genomic stability and other pathways
doi: 10.1001/jamapsychiatry.2019.3259
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AXT showed various effects on HT22 cells, including attenuating mitochondrial dysfunction by regulating the Akt/glycogen synthase kinase (GSK)-3 signaling pathway
1040 ST1326, a selective CPT1A inhibitor, has strong antitumor activity in Burkitt lymphoma and leukemia cell lines, increasing the effectiveness of the Bcl-2 inhibitor ABT-199
Loss of the mitochondrial fatty acid beta-oxidation protein medium-chain acyl-coenzyme A dehydrogenase disrupts oxidative phosphorylation protein complex stability and function
