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Neuroscience 252, 489500

calculated as the sum of reduced GSH and two times the amount of oxidized glutathione (GSH + 2 GSSG)) levels in the serum and in the tumour interstitial fluid (TIF), the extracellular compartment surrounding tumours

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Microglia are initially activated to stage 1 DAM, which are characterized by a downregulation of homeostatic microglial genes including p2ry12 and cx3cr1 , and an upregulation of genes including trem2 , tyrobp and apoe

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Mitochondria-derived methylmalonic acid aggravates ischemia-reperfusion injury by activating reactive oxygen species-dependent ferroptosis