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Furthermore, GluN2C heterozygous and knockout mice exhibited abnormalities in cognition and sensorimotor gating

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Approximately 14 are expected to be reclassified back to Category 1, with roughly 5 remaining restricted due to stronger safety concerns or weaker human data

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[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Kim P.H., Yim H.G., Choi Y.J., Kang B.J., Kim J., Kwon S.M.Cho J.Y

Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to regularly evaluate renal function