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We measured the level of mitochondrial superoxide in PBMCs using the mitochondrial targeted and superoxide specific fluorogenic dye MitoSOXTM Red

doi: 10.1111/odi.12167

Diaz-Latoud C

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Future studies evaluating glutathione with a larger sample size with statistical power to differentiate the association proposal by manic or depressive episodes, as well as the use of NAC as a suicide risk reducer, seem justified

The validated path comes first: sleep hygiene, cognitive behavioral therapy for insomnia (CBT-I), evaluation for an underlying sleep disorder, and established interventions such as melatonin where appropriate