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Astrocytes drive parthanatos via NO/ROS (OH)-induced DNA damage, activating PARP1 to deplete NAD+/ATP and induce energy collapse [261]

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During a total observation period of 30 months, we measured bone turnover markers at regular intervals and BMD annually

Melanocortin peptides inhibit production of proinflammatory cytokines and nitric oxide by activated microglia

Immune function: As a master antioxidant, glutathione supports immune cell production and function, particularly in lymphocytes
