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This exceptional selectivity profile enables researchers to attribute observed effects specifically to NNMT inhibition, rather than off-target activities that plague less specific compounds
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On the other hand, 4 weeks of treatment of quetiapine (300 mg/day) in patients with bipolar depression led to increased levels of Eubacterium rectale , Bifidobacteria, and Bifidobacteria to Enterobacteriacea ratio, having this fact a potential impact on brain function [78]
